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Molecular Biology Institute of Barcelona

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Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
There had been an enduring discrepancy between theoretical and observed measurement of the DNA linking number (ΔLk) constrained by nucleosomes. Here the authors provide measurements of the ΔLk ...
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E proteins play an active role in neurogenesis
Proneural proteins work by binding to specific patterns in the DNA, called E-boxes, with the help of E proteins. E proteins are typically understood to be passive partners, working with each ...
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Cdc48/p97 segregase is modulated by cyclindependent kinase to determine cyclin fate during G1 progression
Cdc48 is overexpressed in many human cancers, and its inhibition arrests lung carcinoma cells in G1. The group of M. Aldea has extend the role of Cdc48 inG1 progression to mammalian cells, where its ...

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Structural Biology (SB) 'María de Maeztu' Unit of Excellence
The Structural Biology Unit is a "María de Maeztu" research unit of excellence which cover distinct aspects of molecular biology from a structural and functional perspective using molecular and structural biology techniques as X-ray diffraction and electron microscopy.
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Molecular Imaging Platform
The Molecular Imaging Platform offers a collection of state-of-the-art instruments that cover a wide light microscopy application spectrum. The systems are available to the IBMB and PCB community, as well as to researchers from other public and private Institutions.

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