Carme Gallego promoted to Investigadora Científica
The IBMB Direction board wants to share the good news that Carme Gallego has been promoted to…
A collaborative study between Dr. Liesa’s laboratory and Janssen R&D demonstrates that decreasing Drp1-mediated mitochondrial fission, using an FDA approved delivery method of siRNA to hepatocytes, exacerbates non-alcoholic steatohepatitis in mice.
The use of siRNA conjugated to N-acetyl-galactosamine (NAG-siRNA) is an approach approved by the FDA…
JmjC family of histone demethylases form nuclear condensates
With our work, we demonstrate that the JmjC-family of histone demethylases contain low complexity domains…
Dr. Liesa’s participated in a new study led by Dr. Wilson at the Center of Regenerative Medicine at Boston University, published in Science Advances titled “CRISPRi interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells”
An iPSC-CRISPRi platform allowed to investigate the functional significance of nine genes associated with Chronic…
JMJD3 intrinsically disordered region links the 3D-genome structure to TGFβ-dependent transcription activation
Summary In our study we demonstrated that TGFb drives multi-enhancer contacts and ultimately gene activation…
News and Views article published at the EMBO Journal about lipid metabolism and lipid droplets
Dr. Liesa was invited by the EMBO Journal to write a News and Views on…
Mad3 modulates the G1 Cdk and acts as a timer in the Start network
Size control is a universal property of cells, and the existence of mechanisms gauging size…
The Basement Membrane controls size and integrity of the Drosophila tracheal tubes
Biological tubes are critical units of most organs in metazoans where they perform vital functions.…
Coordinated changes in gene expression, H1 variant distribution and genome 3D conformation in response to H1 depletion
Researchers of the IBMB have investigated for the first time the genomic distribution of five…
Vall d’Hebron identifies blood testosterone concentration as an accurate predictive marker of COVID-19 survival in men
As age increases in men, the concentration of the hormone in the blood drops and…
Installation and Construction of our IBMBscope: Cryo-Electron Microscope
We got it! Don’t miss the installation of our @IBMBscope: cryo-electron microscope for bio applications.…