DEPARTMENT OF CELL BIOLOGY
The primary goal of the Cell Biology department is to understand major cellular processes and the underlying molecular mechanisms aiming at a better understanding of human disease. These fundamental questions are addressed using different models systems both in vivo (including yeast and mice) and in vitro (cultured cells and purified proteins).
All research groups at the department have a common interest in the mechanistic bases of key cellular functions, and share approaches that include the use of advanced microscopy to analyse molecular dynamics at the single-cell and single-molecule levels, genomic and proteomic methodologies to study gene expression and protein interactions, and state-of-the-art genetic manipulation techniques to test molecular models. Particular biological areas of interest include endocytic trafficking, synaptic plasticity, cell cycle control, signalling, proteasomal regulation, aging and oncogenic transformation.