Skip to content. | Skip to navigation

Personal tools

Publications

  • Forés, M., Simón-Carrasco, L., Ajuria, L., Samper, N., González-Crespo, S., Drosten, M., Barbacid, M. and Jiménez, G. (2017) A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer. PLOS Genetics 11, e1006622.
     
  •  Jiménez, G. (ed) (2017) ERK Signaling: Methods and Protocols. Methods in Molecular Biology Series, Springer, New York.
     
  • Forés, M., Papagianni, A., Rodríguez-Muñoz, L. and Jiménez, G. (2017) Using CRISPR-Cas9 to study ERK signaling in Drosophila. Methods Mol. Biol. 1487, 353-365. 
  • Yang, L., Paul, S., Trieu, K.G., Dent, L.G., Froldi, F., Forés, M., Webster, K., Siegfried, K.R., Kondo, S. Harvey, K., Cheng, L., Jiménez, G., Shvartsman, S. Y. and Veraksa, A. (2016) Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua. Proc. Natl. Acad. Sci. USA 113, 10583-10588.  
  • Samee, Md. A. H., Lim, B., Samper, N., Lu, H., Rushlow, C. A., Jiménez, G., Shvartsman, S. Y. and Sinha, S. (2015) A systematic ensemble approach to thermodynamic modeling of gene expression from sequence data. Cell Systems 1, 396-407.   
  • Jin, Y., Ha, N., Forés, M., Xiang, J., Glaßër, C., Maldera, J., Jiménez, G. and Edgar, B. A. (2015) EGFR/Ras signaling controls Drosophila intestinal stem cell proliferation via Capicua-regulated genes. PLOS Genetics 11, e1005634.    
  • Forés, M., Ajuria, L., Samper, N., Astigarraga, S., Nieva, C., Grossman, R., González-Crespo, S., Paroush, Z. and Jiménez, G. (2015) Origins of context-dependent gene repression by Capicua. PLOS Genetics 11, e1004902.  
     
  • Lim, B., Samper, N., Lu, H., Rushlow, C., Jiménez*, G. and Shvartsman*, S. Y. (2013) Kinetics of gene derepression by ERK signaling. Proc. Natl. Acad. Sci. USA 110, 10330-10335. (*Corresponding authors).  
     
  • Andreu, M. J., Ajuria, L., Samper, N., González-Pérez, E., Campuzano, S., González-Crespo, S. and Jiménez, G. (2012) EGFR-dependent downregulation of Capicua and the establishment of Drosophila dorsoventral polarity. Fly (Austin) 6, 234-239. 
     
  • Helman, A., Lim, B., Andreu, M. J., Kim, Y., Shestkin, T., Lu, H., Jiménez, G., Shvartsman, S. Y. and Paroush, Z. (2012) RTK signaling modulates the Dorsal gradient. Development 139, 3032-3039. 
     
  • Andreu, M. J., González-Pérez, E., Ajuria, L., Samper, N., González-Crespo, S., Campuzano, S. and Jiménez, G. (2012) Mirror represses pipe expression in follicle cells to initiate dorsoventral axis formation in DrosophilaDevelopment 139, 1110-1114. 
     
  • Jiménez, G. Shvartsman S. and Paroush, Z. (2012) The Capicua repressor - a general sensor of RTK signaling in development and disease. J. Cell Sci. 125, 1383-1391.
     
  • Ajuria, L., Nieva, C., Winkler, C., Kuo, D., Samper, N., Andreu, M. J., Helman, A., González-Crespo, S., Paroush, Z., Courey, A. J. and Jiménez, G. (2011) Capicua DNA-binding sites are general response elements for RTK signaling in DrosophilaDevelopment 138, 915-924. 
     
  • Kim, Y., Andreu, M. J., Lim, B., Chung, K., Terayama, M., Jiménez, G., Berg, C. A., Lu, H. and Shvartsman, S. Y. (2011) Gene regulation by MAPK substrate competition. Dev. Cell 20, 880-887. 
     
  • Helman, A., Cinnamon, E., Mezuman, S., Hayouka, Z., von Ohlen, T., Orian, A., Jiménez, G. and Paroush, Z. (2011) Phosphorylation of Groucho mediates RTK feddback inhibition and prolonged pathway target gene expression. Curr. Biol.21, 1102-1110. 
     
  • Kim, Y., Paroush, Z., Nairz, K., Hafen, E., Jiménez*, G. and Shvartsman*, S. Y. (2011) Substrate-dependent control of MAPK phosphorylation in vivo. Mol. Syst. Biol. 7, article number 467.      
     
  • Kim, Y., Coppey, M., Grosman, R., Ajuria, L., Jiménez, G., Paroush, Z. and Shvartsman, S. Y. (2010) MAPK substrate competition integrates patterning signals in the Drosophila embryo. Curr. Biol. 20, 446-451. 
     
  • Cinnamon, E., Helman, R., Ben-Haroush Schyr, R., Orian, A., Jiménez, G. and Paroush, Z. (2008) Multiple RTK pathways down-regulate Groucho-mediated repression in Drosophila embryogenesis. Development 135, 829-837.
     
  • Astigarraga, S., Grossman, R., Díaz-Delfín, J., Caelles, C., Paroush, Z. and Jiménez, G. (2007) A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling. EMBO J26, 668-677.
     
  • Morán, E. and Jiménez, G. (2006) The Tailless nuclear receptor acts as a dedicated repressor in the early Drosophila embryo. Mol. Cell. Biol. 26, 3446-3454.
     
  • Cinnamon, E., Gur-Wahnon, D., Helman, A., St Johnston, D., Jiménez, G and Paroush, Z. (2004) Capicua integrates input from two maternal systems in Drosophila terminal patterning. EMBO J23, 4571-4582. 
      
  • Previous publications
     
  • Jiménez, G., González-Reyes, A. and Casanova, J. (2002) Cell surface proteins Nasrat and Polehole stabilize the Torso-like extracellular determinant in Drosophila oogenesis. Genes & Dev. 16, 913-918.
     
  • Jiménez, G., Guichet, A., Ephrussi, A. and Casanova, J. (2000) Relief of gene repression by Torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning. Genes & Dev. 14, 224-231.
     
  • Eberhard, D., Jiménez, G., Heavy, B. and Busslinger, M. (2000) Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family. EMBO J. 19, 2292-2303.
     
  • Jiménez, G., Verrijzer, C.P. and Ish-Horowicz, D. (1999) A conserved motif in Goosecoid mediates Groucho-dependent repression in Drosophilaembryos. Mol. Cell. Biol. 19, 2080-2087. 
     
  • Jiménez, G. and Ish-Horowicz, D. (1997) A chimeric Enhancer-of-split transcriptional activator drives neural development and achaete-scute expression. Mol. Cell. Biol. 17, 4355-4362.
     
  • Jiménez, G., Paroush, Z. and Ish-Horowicz, D. (1997) Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed. Genes & Dev. 11, 3072-3082.
     
  • Jiménez, G., Pinchin, S.M. and Ish-Horowicz, D. (1996) In vivo interactions of the Drosophila Hairy and Runt transcriptional repressors with target promoters. EMBO J. 15, 7088-7098.
     
  • Jiménez, G., Gale, K.B. and Enver, T. (1992) The mouse beta-globin Locus Control Region: hypersensitive sites 3 and 4. Nucleic Acids Res. 20, 5797-5803.
     
  • Jiménez, G., Griffiths, S., Ford, A.M., Greaves, M.F. and Enver, T. (1992) Activation of the beta-globin Locus Control Region precedes commitment to the erythroid lineage. Proc. Natl. Acad. Sci. USA 89, 10618-10622.

Document Actions